nuclear factor kappa light chain enhancer of activated B cells
Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model.
The purpose of this study was to evaluate the effect of gliclazide on oxidative stress, inflammation, and bone loss in experimental periodontal disease model.Male albino Wistar rats were divided into no binder, binder, and a ligature with 1, 5, and 10 mg / kg of gliclazide group , Maxillary fixed and scanned using micro-computed tomography to measure linear and bone volume / tissue volume (BV / TV) and volumetric bone loss.
Histopathology, the analysis of immunohistochemistry and immunofluorescence performed to test the matrix metalloproteinase-2 (MMP-2), cyclooxygenase 2 (COX-2), cathepsin K, member activator receptor nuclear factor kappa-Β ligand (RANKL), an activator receptor nuclear factor kappa-Β (RANK), osteoprotegerin (OPG) pathway, the migration of macrophage inhibitory factor (MIF), superoxide dismutase-1 (SOD-1), glutathione peroxidase-1 (GPx-1), NFkB p 50 (cytoplasm), NLS NFkB p50 (signal nuclear localization), PI3 kinase and AKT staining. Myeloperoxidase activity, malondialdehyde and glutathione levels, while interleukin-1 beta (IL-1β) and tumor necrosis factor-alpha (TNF-α) levels were evaluated by ultraviolet-visible spectroscopy analysis.
A reverse transcription quantitative polymerase chain reaction was used to measure gene expression of nuclear factor kappa B subunit p50 (NF-kB p50), phosphoinositide 3-kinase (PI3K), protein kinase B (AKT) and F4 / 80.Micro tomography -computed showed that 1 mg / kg of gliclazide treatment reduces bone loss is linear compared with a ligature, 5 mg / kg of gliclazide, and 10 mg / kg of gliclazide treatment.
All concentrations of gliclazide increase bone volume / tissue volume (BV / TV) compared with a binder. Treatment with 1 mg / kg of gliclazide reduce myeloperoxidase activity, malondialdehyde, IL-1β and TNF-α levels (P ≤ 0.05), and results in weak staining for COX-2, cathepsin K, MMP-2, RANK, RANKL , -1 SOD, GPx-1, MIF and PI3K. Furthermore, down-regulation of NF-kB p50, PI3K, Akt, and F4 / 80 were observed, and OPG strong staining after treatment 1 mg / kg of gliclazide treatment.This decreased migration of neutrophils and macrophages, decreased inflammatory response, and decreased bone loss in rats with ligature-induced periodontitis.
Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model.
Preventing gliclazide 5-FU-Induced Oral Mucositis by Reducing Oxidative Stress, Inflammation, and P-Selectin Adhesion Molecules.
Oral mucositis (OM) is one of the main side effects of the treatment of head and neck cancers, particularly radiotherapy and / or chemotherapy. OM is characterized by ulcers, erythema, dysphagia, xerostomia, and increased susceptibility to opportunistic infections. In the perspective of finding a pharmacological therapy to prevent inflammation and ulceration of the OM, the investigation of the pleiotropic effects of commercial drugs are needed, including gliclazide, antidiabetic drugs.
This study aimed to evaluate the effect of gliclazide in experimental models of OM induced by 5-fluorouracil. male hamster pre-treated with oral gliclazide (1, 5, or 10 mg / kg) for 10 days. Cheek pouch samples were subjected to histopathological and immunohistochemical analysis (COX2, iNOS, MMP-2, NF P65, GPx) and imunofluorescence (P-selectin). IL-1β and TNF-α levels, Myeloperoxidase activity (MPO) and the level of malondialdehyde (MDA) was investigated by ultraviolet-visible spectroscopy analysis.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:500-1:5000, IHC:1:25-1:100
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF, ChIP; Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:500, IF:1:50-1:500
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:500-1:5000, IHC:1:5-1:20
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/5000
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/10000
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/40000
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NFKB1 (Ser893). This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NFKB1 (S932). This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody against Phospho-NFKB1 (S893). Recognizes Phospho-NFKB1 (S893) from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000
Description: A polyclonal antibody against Phospho-NFKB1 (S907). Recognizes Phospho-NFKB1 (S907) from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/20000
Description: A polyclonal antibody against Phospho-NFKB1 (S932). Recognizes Phospho-NFKB1 (S932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000
Description: A polyclonal antibody against Phospho-NFKB1 (S337). Recognizes Phospho-NFKB1 (S337) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/40000
Description: A polyclonal antibody against Phospho-NFKB1 (S927). Recognizes Phospho-NFKB1 (S927) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000
Description: A polyclonal antibody against Phospho-NFKB1 (Ser337). Recognizes Phospho-NFKB1 (Ser337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200
Description: A polyclonal antibody against NFKB1 (Ab-907). Recognizes NFKB1 (Ab-907) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (Ser907). Recognizes Phospho-NFKB1 (Ser907) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100
Description: A polyclonal antibody against NFKB1 (Ab-337). Recognizes NFKB1 (Ab-337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
Description: A polyclonal antibody against NFKB1 (Ab-932). Recognizes NFKB1 (Ab-932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA
Description: A polyclonal antibody against NFKB1. Recognizes NFKB1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA
Description: A polyclonal antibody against NFKB1 (Ab-893). Recognizes NFKB1 (Ab-893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (Ser932). Recognizes Phospho-NFKB1 (Ser932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100
Description: A polyclonal antibody against Phospho-NFKB1 (Ser893). Recognizes Phospho-NFKB1 (Ser893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF;IHC:1:50-1:100, IF:1:100-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (Ser927). Recognizes Phospho-NFKB1 (Ser927) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (S337). Recognizes Phospho-NFKB1 (S337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is unconjugated.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 390.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 488.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 565.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 594.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 633.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 655.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 680.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to ATTO 700.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Alkaline Phosphatase.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to APC .
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to APC/Cy7.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Biotin.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Dylight 350.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Dylight 405.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Dylight 488.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Dylight 594.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Dylight 633.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to FITC.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to HRP.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to PE/ATTO 594.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to PerCP.
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to RPE .
Description: A polyclonal antibody for NFKB1 from Human | Mouse. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human NF-kappaB p105/p50. The Antibody is tested and validated for WB, IHC, ICC/IF assays with the following recommended dilutions: WB (1:2000), IHC (1:200), ICC/IF (1:500). This NFKB1 antibody is conjugated to Streptavidin.
Description: A polyclonal antibody against NFKB1 (Ab-893). Recognizes NFKB1 (Ab-893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (Ser932). Recognizes Phospho-NFKB1 (Ser932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100
Description: A polyclonal antibody against NFKB1 (Ab-337). Recognizes NFKB1 (Ab-337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
Description: A polyclonal antibody against NFKB1 (Ab-932). Recognizes NFKB1 (Ab-932) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (Ser893). Recognizes Phospho-NFKB1 (Ser893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF;IHC:1:50-1:100, IF:1:100-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (Ser927). Recognizes Phospho-NFKB1 (Ser927) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (Ser337). Recognizes Phospho-NFKB1 (Ser337) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200
Description: A polyclonal antibody against NFKB1 (Ab-907). Recognizes NFKB1 (Ab-907) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
Description: A polyclonal antibody against Phospho-NFKB1 (Ser907). Recognizes Phospho-NFKB1 (Ser907) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100
NLS NF P50 protein levels were analyzed by western blotting. The group treated with gliclazide at a dose of 10 mg / kg showed the presence of erythema, there was no evidence of erosion, and the absence of mucosal ulceration with a score of 1 (1-2) (p <0.01).
